Lifeline Skin Care Video: Care For Your Skin with Lifeline Skin Care

Stem Cell Skin Care

Born Different.

Lifeline Skin Care® (Lifeline) is a wholly owned subsidiary of International Stem Cell Corporation (OTCBB:ISCO), a publicly traded biotechnology company which has developed a powerful and ethical new stem cell technology called “parthenogenesis”.  ISCO created Lifeline Skin Care® to further develop its discoveries that extracts from human parthenogenetic stem cells had beneficial effects on human skin cells.

International Stem Cell is focused on advancing its human parthenogenetic stem cell technology towards finding treatments for blinding diseases of the eye, liver disease, diseases of the nervous system and diabetes.

Our goal at Lifeline Skin Care® is to help individuals improve the look and feel of their skin by combining the latest discoveries in the fields of stem cell biology, nanotechnology and skin cream formulation technology to create the highest quality, scientifically tested and most effective skin care products.

International Stem Cell Corporation Executives to Speak at Health and Beauty Expo in New York City

International Stem Cell Corporation (OTCBB:ISCO) announced today that Kenneth Aldrich, Chairman of the Board, and Dr. Ruslan Semechkin, President and CEO of Lifeline Skin Care^® (www.lifelineskincare.com), a subsidiary of ISCO, which develops and markets stem cell based anti-aging skincare products, will be addressing recent advances in stem cell technology at the HBA Global Expo being held June 28 – 30 at the Jacob K. Javits Convention Center in New York City. This annual conference attracts more than 15,000 beauty industry professionals and is one of the largest events in the cosmetics and personal care industry. Product development and marketing executives attend the annual HBA conference for education and information on the latest trends in ingredients and raw materials.


Mr. Aldrich is participating in the "Executive Leadership Panel: Generating the Future in the Skin Anti-Aging Category," on Tuesday, June 28, at 1:30 p.m. Dr. Semechkin is presenting at the Expo's Anti-Aging Symposium as an expert on emerging technologies in skincare. Dr. Semechkin's presentation, titled "Stem Cell Derived Growth Factors - the Next Breakthrough in Anti-Aging," is scheduled for Wednesday, June 29, at 1:30 p.m.


International Stem Cell is a world leader in the research and development of parthenogenetic stem cells for therapeutic applications and is developing and commercializing stem cell-based research and cosmetic products through Lifeline Skin Care^®. The first cosmetic products, a defensive day moisture serum and a recovery night moisture serum containing extracts from human parthenogenetic stem cells, were launched in November 2010 and are available for purchase through www.lifelineskincare.com and selected luxury spas across the United States.


About International Stem Cell Corporation
International Stem Cell Corporation is focused on the therapeutic applications of human parthenogenetic stem cells and the development and commercialization of cell-based research and cosmetic products. ISCO's core technology, parthenogenesis, results in the creation of pluripotent human stem cells from unfertilized oocytes (eggs). hpSCs avoid ethical issues associated with the use or destruction of viable human embryos. ISCO scientists have created the first parthenogenic, homozygous stem cell line that can be a source of therapeutic cells with minimal immune rejection after transplantation into hundreds of millions of individuals of differing genders, ages and racial background. This offers the potential to create the first true stem cell bank, UniStemCell™. ISCO also produces and markets specialized cells and growth media for therapeutic research worldwide through its subsidiary Lifeline Cell Technology, and cell-based skin care products through its subsidiary Lifeline Skin Care. More information is available at www.internationalstemcell.com.


To subscribe to receive ongoing corporate communications, please click on the following link: http://www.b2i.us/irpass.asp?BzID=1468&to=ea&s=0.


Forward-looking Statements
Statements pertaining to anticipated developments, product development and marketing plans, and other opportunities for the company and its subsidiaries, along with other statements about the future expectations, beliefs, goals, plans, or prospects expressed by management constitute forward-looking statements. Any statements that are not historical fact (including, but not limited to statements that contain words such as "will," "believes," "plans," "anticipates," "expects," "estimates,") should also be considered to be forward-looking statements. Forward-looking statements involve risks and uncertainties, including, without limitation, risks inherent in the development and/or commercialization of potential products, competition, regulatory approvals, need and ability to obtain future capital, application of capital resources among competing uses, and maintenance of intellectual property rights. Actual results may differ materially from the results anticipated in these forward-looking statements and as such should be evaluated together with the many uncertainties that affect the company's business, particularly those mentioned in the cautionary statements found in the company's Securities and Exchange Commission filings. The company disclaims any intent or obligation to update forward-looking statements.



International Stem Cell Corporation
760-940-6383
Kenneth C. Aldrich, Chairman
kaldrich@intlstemcell.com
Ruslan Semechkin, PhD
Vice President, ISCO
President and CEO, Lifeline Skin Care
ras@intlstemcell.com
or:
Lippert/Heilshorn & Associates
Don Markley, 310-691-7100
dmarkley@lhai.com

International Stem Cell Corporation Updates on 2010 Initial Product Launch of its Lifeline Skin Care Products

International Stem Cell Corporation (OTCBB:ISCO), www.internationalstemcell.com, announced today that its wholly owned subsidiary Lifeline Skin Care, Inc. ("LSC"), has now completed its evaluation of the highly successful trial launch of its new stem cell skin care product line in November and December 2010, and will move forward with its general marketing program.

Lifeline Skin Care products contain parthenogenetic stem cell extract and were developed by the ISCO research team in collaboration with world recognized cosmetic chemists. The breakthrough products deliver leading advances in skin rejuvenation technology that help to prevent and repair damaged skin. The products are available through our online store at www.lifelineskincare.com.

"Sales to date have greatly exceeded our expectations for the trial launch. These initial sales resulted from a very limited product offering made to subscribers of only one of the several newsletters of our marketing partner, John Mauldin, plus a small direct mailing to interested parties and ISCO's shareholders who had signed up for general corporate information through the ISCO website," said Dr. Ruslan Semechkin, CEO of Lifeline Skin Care.

Lifeline Skin Care is now ready to move forward to the next phase of distribution, which will commence near the end of March. That phase will consist initially of a customer solicitation conducted by John Mauldin's specialty Internet and direct response marketing organization. "We almost never endorse or sell a retail product," said Mr. Mauldin, "but the results of both our informal testing and the company's formal studies have convinced us that the Lifeline Skin Care products really are a game-changing advance in skin care. I have not seen such a strong response in online marketing in the last ten years. We are all very excited and proud to be involved."

Kenneth Aldrich, Chairman of ISCO, issued a cautionary comment to its investors. "We are incredibly excited by the prospects of this new product from our Lifeline Skin Care subsidiary. Selling over 7,000 bottles through a very limited trial launch, as we have done, represents a significant first step, but it would be imprudent for us to base projections of future sales or profits on a sample base of this size."

ISCO investors should note that under ISCO's current revenue recognition policy, a large portion of the Q-4 2010 sales will not be included as revenue in the financial statements for the year ended December 31, 2010. Sales of these products meet our revenue recognition criteria after our 30 day product guarantee period has been completed.

ABOUT INTERNATIONAL STEM CELL CORPORATION (ISCO.OB)

International Stem Cell Corporation is a California-based biotechnology company focused on therapeutic and research products. ISCO's core technology, parthenogenesis, results in creation of pluripotent human stem cells from unfertilized oocytes (eggs). These proprietary cells avoid ethical issues associated with use or destruction of viable human embryos and, unlike most other major stem cell types, can be immune matched and be a source of therapeutic cells with minimal rejection after transplantation into hundreds of millions of individuals of differing racial groups. ISCO also produces and markets specialized cells and growth media for therapeutic research worldwide through its subsidiary, Lifeline Cell Technology, and has developed cell based skin care products through its subsidiary, Lifeline Skin Care. ISCO is advancing novel human stem cell-based therapies where cells have been proven to be efficacious but traditional small molecule and protein therapeutics have not. More information is available on ISCO's website, www.internationalstemcell.com.

To subscribe to receive ongoing corporate communications please click on the following link: http://www.b2i.us/irpass.asp?BzID=1468&to=ea&s=0.

FORWARD-LOOKING STATEMENTS

Statements pertaining to anticipated developments, product marketing plans, the potential benefits of collaborations, affiliations, and other opportunities for the company and its subsidiaries, along with other statements about the future expectations, beliefs, goals, plans, or prospects expressed by management constitute forward-looking statements. Any statements that are not historical fact (including, but not limited to statements that contain words such as "will," "believes," "plans," "anticipates," "expects," "estimates,") should also be considered to be forward-looking statements. Forward-looking statements involve risks and uncertainties, including, without limitation, risks inherent in the development and/or commercialization of potential products and the management of collaborations, regulatory approvals, need and ability to obtain future capital, application of capital resources among competing uses, and maintenance of intellectual property rights. Actual results may differ materially from the results anticipated in these forward-looking statements and as such should be evaluated together with the many uncertainties that affect the company's business, particularly those mentioned in the cautionary statements found in the company's Securities and Exchange Commission filings. The company disclaims any intent or obligation to update forward-looking statements.

Key Words: Stem cells, parthenogenesis, biotechnology, skin care

International Stem Cell Corporation
Kenneth C. Aldrich, Chairman
1-760-940-6383
kaldrich@intlstemcell.com
or
Lifeline Skin Care, Inc.
Ruslan Semechkin, PhD, President & CEO
Vice President, ISCO
ras@intlstemcell.com

"A Little Egg On the Face" - LifeLine Skin Care Stem Cell Cream Article

"A Little Egg On the Face" by Rebecca Tolin (read San Diego Magazine article here )

Women have been known to slather their faces with fruit, fish oil, foreskin (uh huh, the target of circumcision) and even the neurotoxin that causes botulism — all in the name of looking pretty. Now an Oceanside biotech has another novel ingredient for the aging-averse: stem cells from unfertilized human eggs.

“It’s not like a woman donated eggs in Encinitas and three months later it’s in someone’s skin in L.A.,” explains Brian Lundstrom, president of International Stem Cell Corporation (ISSC) in Oceanside, parent company of Lifeline Skin Care. It’s more like this: Women go to in-vitro fertilization clinics to get pregnant. There are often leftover eggs from that process. Researchers select stem cells, grow billions of them, and extract the bits that skin loves, such as growth factors — with permission from the donors, of course. Scientists then whip ’em up with antioxidants and sell the stuff in a slick plastic tube for about the cost of a month’s supply of Frappuccinos.

Is this a noncaffeinated fountain of youth? Ruslan Semechkin, the CEO of Lifeline and a biologist by training, says an eight-week study showed the day-and-night serum combo reduced the number and depth of wrinkles and made skin brighter, tighter and moister — though he wouldn’t say by how much. (Semechkin is 25, has the olive-tinged skin of a baby and admits a complexion of his variety doesn’t need this heavy hitter.)
Even in the stem cell world, youth is coveted. Lundstrom says stem cells taken from unfertilized eggs — the very seeds of life — are the youngest around and can become any cell in the human body. This is the first time such stem cell fragments have found their way into beauty cream, he explains. And because the eggs aren’t fertilized, they bypass the embryo controversy.

Someday, movement in the paralyzed and memory in the aged could be restored by using such cells; ISSC has already grown a human cornea that could cure blindness in people with eye damage. These breakthroughs may be dec­ades away, but ISSC’s “cosmeceuticals” are just the beginning. Profits from pocketbooks of the age-obsessed will fund the biotech’s research for other therapeutic drugs. So if you’re considering spending a small fortune to plump things up, you could call it a contribution to science.

Lifeline Defensive Day Moisture Serum sells for $155 and Lifeline Recovery Night Moisture Serum costs $185. It’s available at lifelineskincare.com.